COVID-19 y enfermedad trombótica o tromboembólica: implicaciones en la prevención, el tratamiento antitrombótico y el seguimiento. Revisión de actualización de JACC
Behnood Bikdelia,b,c, Mahesh V. Madhavana,c, David Jimenezd, Taylor Chuicha, Isaac Dreyfusa, Elissa Driggina, Caroline Der Nigoghossiana, Walter Agenoe, Mohammad Madjidf, Yutao Guog, Liang V. Tangh, Yu Huh, Jay Girii,j,k, Mary Cushmanl, Isabelle Quérém, Evangelos P. Dimakakosn, C. Michael Gibsono,p, Giuseppe Lippiq, Emmanuel J. Favaloror,s, Jawed Fareedt..., Joseph A. Capriniu, Alfonso J. Tafuru,v, John R. Burtona, Dominic P. Francesec, Elizabeth Y. Wanga, Anna Falangaw, Claire McLintockx, Beverley J. Hunty, Alex C. Spyropoulosz, Geoffrey D. Barnesaa,bb, John W. Eikelboomcc, Ido Weinbergo,dd, Sam Schulmanee,ff,gg, Marc Carrierhh, Gregory Piazzao,ii, Joshua A. Beckmanjj, P. Gabriel Stegkk,ll,mm, Gregg W. Stonec,nn, Stephan Rosenkranzoo, Samuel Z. Goldhabero,ii, Sahil A. Parikhc,a, Manuel Monrealpp, Harlan M. Krumholzb,qq,rr, Stavros V. Konstantinidesss, Jeffrey I. Weitzff,gg, Gregory Y.H. Liptt,uuVer más
a NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, Nueva York, Nueva York.
aa Center for Bioethics and Social Science in Medicine, University of Michigan, Ann Arbor, Michigan.
b Center for Outcomes Research and Evaluation (CORE), Yale School of Medicine, New Haven, Connecticut.
bb Frankel Cardiovascular Center, University of Michigan, Ann Arbor, Michigan.
c Clinical Trials Center, Cardiovascular Research Foundation, Nueva York, Nueva York.
cc Population Health Research Institute, Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canadá.
d Departamento de Neumología, Hospital Ramón y Cajal y Departamento de Medicina, Universidad de Alcalá (Instituto de Ramón y Cajal de Investigación Sanitaria), Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Madrid, España.
dd Massachusetts General Hospital, Boston, Massachusetts.
e Department of Medicine and Surgery, University of Insubria, Varese, Italia.
ee Department of Obstetrics and Gynecology, I.M. Sechenov First Moscow State Medical University, Moscú, Rusia.
f McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas.
ff McMaster University, Hamilton, Ontario, Canadá.
g Department of Cardiology, Chinese PLA General Hospital, Beijing, China.
gg Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canadá.
h Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
hh Ottawa Hospital Research Institute, Ottawa, Ontario, Canadá.
i Cardiovascular Division, Hospital of the University of Pennsylvania, Filadelfia, Pensilvania.
ii Brigham and Women´s Hospital, Boston, Massachusetts.
j Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center, Leonard Davis Institute of Health Economics, University of Pennsylvania, Filadelfia, Pensilvania.
jj Vanderbilt University School of Medicine, Nashville, Tennessee.
k Corporal Michael J. Crescenz VA Medical Center, Filadelfia, Pensilvania.
kk INSERM U1148, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, FACT (French Alliance for Cardiovascular Trials), París, Francia.
l University of Vermont Medical Center, Burlington, Vermont.
ll Université Paris, París, Francia.
m Department of Vascular Medicine, University of Montpellier, Centre Hospitalier Universitaire Montpellier, InnoVTE F-CRIN Network, Montpellier, Francia.
mm Royal Brompton Hospital, Imperial College London, Londres, Reino Unido.
n Oncology Unit GPP, Sotiria General Hospital Athens School of Medicine, Atenas, Grecia.
nn Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Nueva York, Nueva York.
o Harvard Medical School, Boston, Massachusetts.
oo Cologne Cardiovascular Research Center, Heart Center, Department of Cardiology, University of Cologne, Colonia, Alemania.
p Beth Israel Deaconess Medical Center, Boston, Massachusetts.
pp Departamento de Medicina Interna, Hospital Universitari Germans Trias i Pujol, Universidad Católica San Antonio de Murcia, Barcelona, España.
q Laboratory of Clinical Chemistry and Hematology, University Hospital of Verona, Verona, Italia.
qq Department of Health Policy and Administration, Yale School of Public Health, New Haven, Connecticut.
r Haematology Laboratory, Institute of Clinical Pathology and Medical Research, NSW Health Pathology, Westmead Hospital, Westmead, New South Wales, Australia.
rr Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
s Sydney Centres for Thrombosis and Haemostasis, Westmead, New South Wales, Australia.
ss Center for Thrombosis and Hemostasis, Johannes Gutenberg University of Mainz, Mainz, Alemania.
t Loyola University Medical Center, Chicago, Illinois.
tt Liverpool Centre for Cardiovascular Science, Liverpool Heart and Chest Hospital, University of Liverpool, Liverpool, Reino Unido.
u Pritzker School of Medicine, University of Chicago, Chicago, Illinois.
uu Aalborg University, Aalborg, Dinamarca.
v Division of Vascular Medicine, Department of Medicine, NorthShore University HealthSystem, Skokie, Illinois.
w Department of Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, University of Milan Bicocca, Bérgamo, Italia.
x Auckland City Hospital, Auckland, Nueva Zelanda.
y St Thomas´ Hospital, Londres, Reino Unido.
z Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hofstra University, Hempstead, Nueva York.
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"etiqueta" => "f" "identificador" => "881" ] 11 => array:3 [ "entidad" => "McMaster University, Hamilton, Ontario, Canadá." "etiqueta" => "ff" "identificador" => "907" ] 12 => array:3 [ "entidad" => "Department of Cardiology, Chinese PLA General Hospital, Beijing, China." "etiqueta" => "g" "identificador" => "882" ] 13 => array:3 [ "entidad" => "Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canadá." "etiqueta" => "gg" "identificador" => "908" ] 14 => array:3 [ "entidad" => "Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China." "etiqueta" => "h" "identificador" => "883" ] 15 => array:3 [ "entidad" => "Ottawa Hospital Research Institute, Ottawa, Ontario, Canadá." "etiqueta" => "hh" "identificador" => "909" ] 16 => array:3 [ "entidad" => "Cardiovascular Division, Hospital of the University of Pennsylvania, Filadelfia, Pensilvania." "etiqueta" => "i" "identificador" => "884" ] 17 => array:3 [ "entidad" => "Brigham and Women´s Hospital, Boston, Massachusetts." "etiqueta" => "ii" "identificador" => "910" ] 18 => array:3 [ "entidad" => "Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center, Leonard Davis Institute of Health Economics, University of Pennsylvania, Filadelfia, Pensilvania." "etiqueta" => "j" "identificador" => "885" ] 19 => array:3 [ "entidad" => "Vanderbilt University School of Medicine, Nashville, Tennessee." "etiqueta" => "jj" "identificador" => "911" ] 20 => array:3 [ "entidad" => "Corporal Michael J. Crescenz VA Medical Center, Filadelfia, Pensilvania." "etiqueta" => "k" "identificador" => "886" ] 21 => array:3 [ "entidad" => "INSERM U1148, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, FACT (French Alliance for Cardiovascular Trials), París, Francia." "etiqueta" => "kk" "identificador" => "912" ] 22 => array:3 [ "entidad" => "University of Vermont Medical Center, Burlington, Vermont." "etiqueta" => "l" "identificador" => "887" ] 23 => array:3 [ "entidad" => "Université Paris, París, Francia." "etiqueta" => "ll" "identificador" => "913" ] 24 => array:3 [ "entidad" => "Department of Vascular Medicine, University of Montpellier, Centre Hospitalier Universitaire Montpellier, InnoVTE F-CRIN Network, Montpellier, Francia." "etiqueta" => "m" "identificador" => "888" ] 25 => array:3 [ "entidad" => "Royal Brompton Hospital, Imperial College London, Londres, Reino Unido." "etiqueta" => "mm" "identificador" => "914" ] 26 => array:3 [ "entidad" => "Oncology Unit GPP, Sotiria General Hospital Athens School of Medicine, Atenas, Grecia." "etiqueta" => "n" "identificador" => "889" ] 27 => array:3 [ "entidad" => "Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Nueva York, Nueva York." "etiqueta" => "nn" "identificador" => "915" ] 28 => array:3 [ "entidad" => "Harvard Medical School, Boston, Massachusetts." "etiqueta" => "o" "identificador" => "890" ] 29 => array:3 [ "entidad" => "Cologne Cardiovascular Research Center, Heart Center, Department of Cardiology, University of Cologne, Colonia, Alemania." "etiqueta" => "oo" "identificador" => "916" ] 30 => array:3 [ "entidad" => "Beth Israel Deaconess Medical Center, Boston, Massachusetts." "etiqueta" => "p" "identificador" => "891" ] 31 => array:3 [ "entidad" => "Departamento de Medicina Interna, Hospital Universitari Germans Trias i Pujol, Universidad Católica San Antonio de Murcia, Barcelona, España." "etiqueta" => "pp" "identificador" => "917" ] 32 => array:3 [ "entidad" => "Laboratory of Clinical Chemistry and Hematology, University Hospital of Verona, Verona, Italia." "etiqueta" => "q" "identificador" => "892" ] 33 => array:3 [ "entidad" => "Department of Health Policy and Administration, Yale School of Public Health, New Haven, Connecticut." "etiqueta" => "qq" "identificador" => "918" ] 34 => array:3 [ "entidad" => "Haematology Laboratory, Institute of Clinical Pathology and Medical Research, NSW Health Pathology, Westmead Hospital, Westmead, New South Wales, Australia." "etiqueta" => "r" "identificador" => "893" ] 35 => array:3 [ "entidad" => "Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut." "etiqueta" => "rr" "identificador" => "919" ] 36 => array:3 [ "entidad" => "Sydney Centres for Thrombosis and Haemostasis, Westmead, New South Wales, Australia." "etiqueta" => "s" "identificador" => "894" ] 37 => array:3 [ "entidad" => "Center for Thrombosis and Hemostasis, Johannes Gutenberg University of Mainz, Mainz, Alemania." "etiqueta" => "ss" "identificador" => "920" ] 38 => array:3 [ "entidad" => "Loyola University Medical Center, Chicago, Illinois." "etiqueta" => "t" "identificador" => "895" ] 39 => array:3 [ "entidad" => "Liverpool Centre for Cardiovascular Science, Liverpool Heart and Chest Hospital, University of Liverpool, Liverpool, Reino Unido." "etiqueta" => "tt" "identificador" => "921" ] 40 => array:3 [ "entidad" => "Pritzker School of Medicine, University of Chicago, Chicago, Illinois." "etiqueta" => "u" "identificador" => "896" ] 41 => array:3 [ "entidad" => "Aalborg University, Aalborg, Dinamarca." "etiqueta" => "uu" "identificador" => "922" ] 42 => array:3 [ "entidad" => "Division of Vascular Medicine, Department of Medicine, NorthShore University HealthSystem, Skokie, Illinois." "etiqueta" => "v" "identificador" => "897" ] 43 => array:3 [ "entidad" => "Department of Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, University of Milan Bicocca, Bérgamo, Italia." "etiqueta" => "w" "identificador" => "898" ] 44 => array:3 [ "entidad" => "Auckland City Hospital, Auckland, Nueva Zelanda." "etiqueta" => "x" "identificador" => "899" ] 45 => array:3 [ "entidad" => "St Thomas´ Hospital, Londres, Reino Unido." "etiqueta" => "y" "identificador" => "900" ] 46 => array:3 [ "entidad" => "Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hofstra University, Hempstead, Nueva York." "etiqueta" => "z" "identificador" => "901" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:1 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => """ RESUMENLa enfermedad por coronavirus-2019 (COVID-19), una enfermedad respiratoria vírica causada por el coronavirus del síndrome respiratorio agudo grave de tipo 2 (SARS-CoV-2), puede predisponer a los pacientes a sufrir una enfermedad trombótica, tanto en la circulación venosa como en la arterial, como consecuencia de la inflamación excesiva, la activación plaquetaria, la disfunción endotelial y la estasis. Además, muchos pacientes a los que se administra un tratamiento antitrombótico por una enfermedad trombótica pueden padecer la COVID-19, y ello puede tener consecuencias por lo que respecta a la elección, posología y vigilancia analítica del tratamiento antitrombótico. Además, en un tiempo en el que se centra mucho el interés en la COVID-19, es crucial considerar cómo puede optimizarse la tecnología disponible para atender a los pacientes sin COVID-19 que sufren una enfermedad trombótica. En este artículo, los autores examinan los conocimientos actualmente existentes sobre la patogenia, epidemiología, tratamiento y resultados de los pacientes con COVID-19 que sufren una trombosis venosa o arterial, de los pacientes con una enfermedad trombótica preexistente que presentan la COVID-19, y de los pacientes en los que es necesaria la prevención o la asistencia para una enfermedad trombótica durante la pandemia de la COVID-19. ((J Am Coll Cardiol 2020;75:2950–73) © 2020 American College of Cardiology Foundation.\n \t\t\t\t\t\t """ ] ] ] "idiomaDefecto" => "es" "url" => "/X7351097/0000000100000014/v1_202009161238/XX735109720004320/v0_202009161238/es/main.assets" "Apartado" => array:4 [ "identificador" => "72274" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Investigaciones originales" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/X7351097/0000000100000014/v1_202009161238/XX735109720004320/v0_202009161238/es/main.pdf?idApp=UINPBA000085&text.app=https://jacc.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/XX735109720004320?idApp=UINPBA000085" ]
Información del artículo
ISSN: X7351097Idioma original: Español
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